教職人員
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顧記華
研究領域：藥物作用機轉研究
本職：教授
| 最高學歷 | : | 台大藥學系(34屆，1986-1990) 台大藥理學研究所碩士(1990-1992) 台大藥理學研究所博士(1992-1996) |
| 經歷 | : | 2010/8月~ 教授, 台大藥學系 2008/7月~2009/7月 Visiting Associate Professor, The Ohio State University 2004/8月~2010/7月 副教授, 台大藥學系 2000/2月~2004/7月 助理教授, 台大藥學系 |
| 榮譽 | : | 台灣大學教學傑出教師獎(2003年) 景康青年教師獎 台灣大學教學傑出教師獎(2008年) 台灣大學教學優良教師獎(2013-2016年) |
| 研究領域 | : | 藥物作用機轉研究 |
| 研究方向 | : | 抗癌藥物基礎與應用研究、抗癌作用機制研究、老藥新用作用機制研究 |
| 研究題目 | : | 1. 抗癌活性之藥理藥效評估 2. 抗癌藥物作用機轉研究 |
| 老師的話 | : | 希望在為人處世上要永遠保有三顆心: 謙卑的心, 善良的心, 感恩的心。 |
| 研究室要求 | : | 樂觀、積極、負責任 |
| 招生名額 | : | 分子醫藥組博士班一名 醫藥生技組碩士班(甄試+招生考試)擬招收新生2名 |
Establishing a noncanonical zinc-binding group as a selective histone deacetylase inhibitor and possible novel anticancer agent.
(2025-10) Huang, Hsuan-Chun ; Chen, Tse-Yu ; Yeh, Tsung-Yu ; Yu, Min-Hsuan ; Wu, Sian-Siou ; Li, Guang-Yi ; Chen, Bo-Yu ; MIAO-HSIA LIN ; Lin, Ching-Jung ; Hsu, Jui-Ling ; JIH-HWA GUH ; CHAO-WU YU
Design and synthesis of novel HDAC6 inhibitor dimer as HDAC6 degrader for cancer treatment by palladium catalysed dimerisation.
(2025) Lin, Ching ; Hsu, Jui-Ling ; Hsu, Yu-Tung ; Fan, Kuo-Chen ; Wu, Sian-Siou ; MIAO-HSIA LIN ; JIH-HWA GUH ; CHAO-WU YU
Doxazosin inhibits vasculogenic mimicry in human non‑small cell lung cancer through inhibition of the VEGF‑A/VE‑cadherin/mTOR/MMP pathway
(2024-04) Hsu, Jui-Ling ; Leu, Wohn-Jenn ; LIH-CHING HSU ; Hsieh, Chia-Hsun ; JIH-HWA GUH
Cardenolide glycosides sensitize gefitinib-induced apoptosis in non-small cell lung cancer: inhibition of Na+/K+-ATPase serving as a switch-on mechanism
(2024-03-07) Du, Chi-Min ; Leu, Wohn-Jenn ; Jiang, Yi-Huei ; Chan, She-Hung ; Chen, Ih-Sheng ; Chang, Hsun-Shuo ; LIH-CHING HSU ; Hsu, Jui-Ling ; JIH-HWA GUH
A novel HDAC6 inhibitor interferes microtubule dynamics and spindle assembly checkpoint and sensitizes cisplatin-induced apoptosis in castration-resistant prostate cancer
(2024-02-20) Ye, Pei-Chen ; Leu, Wohn-Jenn ; Yeh, Tsung-Yu ; Hsu, Yu-Tung ; Lin, Yi-Chin ; Wei, Zi-Yuan ; Chen, Yi-Chin ; Chiang, Yi-Chang ; Hsu, Jui-Ling ; Chan, She-Hung ; LIH-CHING HSU ; JI-WANG CHERN ; CHAO-WU YU ; JIH-HWA GUH
(2025-10) Huang, Hsuan-Chun ; Chen, Tse-Yu ; Yeh, Tsung-Yu ; Yu, Min-Hsuan ; Wu, Sian-Siou ; Li, Guang-Yi ; Chen, Bo-Yu ; MIAO-HSIA LIN ; Lin, Ching-Jung ; Hsu, Jui-Ling ; JIH-HWA GUH ; CHAO-WU YU
Design and synthesis of novel HDAC6 inhibitor dimer as HDAC6 degrader for cancer treatment by palladium catalysed dimerisation.
(2025) Lin, Ching ; Hsu, Jui-Ling ; Hsu, Yu-Tung ; Fan, Kuo-Chen ; Wu, Sian-Siou ; MIAO-HSIA LIN ; JIH-HWA GUH ; CHAO-WU YU
Doxazosin inhibits vasculogenic mimicry in human non‑small cell lung cancer through inhibition of the VEGF‑A/VE‑cadherin/mTOR/MMP pathway
(2024-04) Hsu, Jui-Ling ; Leu, Wohn-Jenn ; LIH-CHING HSU ; Hsieh, Chia-Hsun ; JIH-HWA GUH
Cardenolide glycosides sensitize gefitinib-induced apoptosis in non-small cell lung cancer: inhibition of Na+/K+-ATPase serving as a switch-on mechanism
(2024-03-07) Du, Chi-Min ; Leu, Wohn-Jenn ; Jiang, Yi-Huei ; Chan, She-Hung ; Chen, Ih-Sheng ; Chang, Hsun-Shuo ; LIH-CHING HSU ; Hsu, Jui-Ling ; JIH-HWA GUH
A novel HDAC6 inhibitor interferes microtubule dynamics and spindle assembly checkpoint and sensitizes cisplatin-induced apoptosis in castration-resistant prostate cancer
(2024-02-20) Ye, Pei-Chen ; Leu, Wohn-Jenn ; Yeh, Tsung-Yu ; Hsu, Yu-Tung ; Lin, Yi-Chin ; Wei, Zi-Yuan ; Chen, Yi-Chin ; Chiang, Yi-Chang ; Hsu, Jui-Ling ; Chan, She-Hung ; LIH-CHING HSU ; JI-WANG CHERN ; CHAO-WU YU ; JIH-HWA GUH
Study of Active Extract from Traditional Chinese Medicine Formula on Anti-Non-Small Cell Lung Cancer Effect
(2023-08-01～) JIH-HWA GUH
Study of Active Extract from Traditional Chinese Medicine Formula on Anti-Non-Small Cell Lung Cancer Effect
(2022-08-01～) JIH-HWA GUH
Study of Active Extract from Traditional Chinese Medicine Formula on Anti-Non-Small Cell Lung Cancer Effect
(2021-08-01～) JIH-HWA GUH
Design, Synthesis and Mechanism Study of Anticancer Agents on Akt Inhibition and Lipid Raft Disturbing against Human Hormone-Refractory Metastatic Prostate Cancer
(2020-08-01～) JIH-HWA GUH
Study of Synergistic Anticancer Mechanism of Combination Treatment between Sildenafil and Doxorubicin in Hormone-Refractory Prostate Cancer – Crucial Role of Dna Repair and Development of Sildenafil Derivatives without Cardiovascular Adverse Effects
(2019-08-01～) JIH-HWA GUH
(2023-08-01～) JIH-HWA GUH
Study of Active Extract from Traditional Chinese Medicine Formula on Anti-Non-Small Cell Lung Cancer Effect
(2022-08-01～) JIH-HWA GUH
Study of Active Extract from Traditional Chinese Medicine Formula on Anti-Non-Small Cell Lung Cancer Effect
(2021-08-01～) JIH-HWA GUH
Design, Synthesis and Mechanism Study of Anticancer Agents on Akt Inhibition and Lipid Raft Disturbing against Human Hormone-Refractory Metastatic Prostate Cancer
(2020-08-01～) JIH-HWA GUH
Study of Synergistic Anticancer Mechanism of Combination Treatment between Sildenafil and Doxorubicin in Hormone-Refractory Prostate Cancer – Crucial Role of Dna Repair and Development of Sildenafil Derivatives without Cardiovascular Adverse Effects
(2019-08-01～) JIH-HWA GUH