Identification of pyrazole scaffold inhibitors targeting cyclin-dependent kinase 8 for potential use in pulmonary fibrosis (2025-07) Lin, Tony Eight ; Hsu, Kai-Cheng ; Chou, Ching-Hsuan ; Tsai, En-Yun ; Wu, Yi-Wen ; Sung, Tzu-Ying ; Hsu, Jui-Yi ; Hsieh, Jui-Hua ; Yen, Shih-Chung ; Chang, Yu-Wei ; Pan, Shiow-Lin ; Huang, Wei-Jan ; CHIA-RON YANG
Structural optimization and biological evaluation of indolin-2-one derivatives as novel CDK8 inhibitors for idiopathic pulmonary fibrosis (2025-03) Hsu, Jui-Yi ; Hsu, Kai-Cheng ; Chou, Ching-Hsuan ; He, Tzu-Ying ; Lin, Tony Eight ; Sung, Tzu-Ying ; Yen, Shih-Chung ; Hsieh, Jui-Hua ; CHIA-RON YANG ; Huang, Wei-Jan
Identification of a Potent CDK8 Inhibitor Using Structure-Based Virtual Screening. (2025-01-13) Lin, Tony Eight ; Chou, Ching-Hsuan ; Wu, Yi-Wen ; Sung, Tzu-Ying ; Hsu, Jui-Yi ; Yen, Shih-Chung ; Hsieh, Jui-Hua ; Chang, Yu-Wei ; Pan, Shiow-Lin ; Huang, Wei-Jan ; Hsu, Kai-Cheng ; CHIA-RON YANG
The Cyclin-Dependent Kinase 8 Inhibitor E966–0530–45418 Attenuates Pulmonary Fibrosis In Vitro and In Vivo (2025) Chou, Ching-Hsuan ; Huang, Wei-Jan ; Hsu, Kai-Cheng ; Hsu, Jui-Yi ; Lin, Tony Eight ; CHIA-RON YANG
An ensemble machine learning model generates a focused screening library for the identification of CDK8 inhibitors. (2024-06) Lin, Tony Eight ; Yen, Dyan ; HuangFu, Wei-Chun ; Wu, Yi-Wen ; Hsu, Jui-Yi ; Yen, Shih-Chung ; Sung, Tzu-Ying ; Hsieh, Jui-Hua ; Pan, Shiow-Lin ; CHIA-RON YANG ; Huang, Wei-Jan ; Hsu, Kai-Cheng
Ai-Assisted Drug Repurposing to Accelerate the Development of Inhalable Combination Therapy for Idiopathic Pulmonary Fibrosis (2025-09-01~) CHIA-RON YANG
The Study on the Development of 4-(Pyridin-4-Yloxy)Aniline Structural Derivatives for the Treatment of Renal Fibrosis and Investigation of the Mechanism (2025-08-01~) CHIA-RON YANG
Novel Cyclin-Dependent Kinase 8 Inhibitor Lead Compound Development and Application in Pulmonary Fibrosis (2024-08-01~) CHIA-RON YANG
Novel Cyclin-Dependent Kinase 8 Inhibitor Lead Compound Development and Application in Pulmonary Fibrosis (2023-08-01~) CHIA-RON YANG
Characterization of the Mechanisms of Histone Deacetylase 6 in Glioblastoma Multiforme Growth and the Specific Histone Deacetylase 6 Inhibitor Lead Compound Development (2022-08-01~) CHIA-RON YANG