教職人員
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梁碧惠
研究領域：設計與合成新藥、藥物化學、有機化學、生物活性評估
本職：教授
| 最高學歷 | : | 國立臺灣大學藥學系學士 國立臺灣大學藥學所博士 |
| 經歷 | : | *合聘，中研院基因體中心 *董事及工業藥學委員會主委, 台灣藥學會 2024年起 *秘書長, 西太平洋藥事論壇 2025起 *訪問學者, 美國加州大學聖地牙哥分校 2019 *副教授, 臺大藥學系 *助理教授,臺大藥學系 ＊博士後研究員, 中研院及The Scripps Research Institute |
| 榮譽 | : | 2024 臺北生技獎技術合作獎銀獎 2024 國科會傑出研究獎 (112學年度) 2023 第20屆未來科技獎-得獎題目：the Development of Small Molecule-Drug Conjugation 2022 第19屆未來科技獎-得獎題目：皂苷佐劑 2022 2022 年國科會小聯盟產學合作獎 2022 第二屆吳火獅醫學獎 2022 臺灣大學教學優良獎 2022 國科會獲選補助參與美國生物大會 US Bio (San Diego, CA, USA) 2021 第18屆國家新創獎，題目:新穎皂苷佐劑 2021 科技部未來科技獎，題目：新冠肺炎之老藥新用 2021 臺灣大學教學優良獎 2021 獲得Spark Asia推薦於臺灣BioAisa報告（the Spark Asia Showcase and Entrepreneur Pitch） 2020 Select as a Spark Presenter in BioInvestor Forum 2020 2020 科技部年經學者計畫 (2020.8–2023.7) 2020 青杏醫學獎 2018 臺灣大學教學優良獎 2016 臺灣大學教學優良獎 2015 景康基金會年輕教師獎 2015 國科會大專生研究計畫指導獎 2015 新竹縣文山國小第一屆傑出校友獎 2014 美國化學會藥物化學傑出口頭報告獎（at the 9th International Symposium for Chinese Medicinal Chemists 2011 國科會大專生研究計畫指導獎 2011 臺灣大學教學優良獎 |
| 研究領域 | : | 設計與合成新藥、藥物化學、有機化學、生物活性評估 |
| 研究方向 | : | 本研究室著重在使用藥物有機合成為工具，藥物化學的概念進行新藥的設計與合成，解決醫學和生物上的問題。研究的方向為設計與合成小分子藥物在癌症、免疫活化、退化性關節炎藥物的開發。 |
| 老師的話 | : | 對科學充滿好奇心 持續堅持努力 |
| 研究室要求 | : | 要有團隊合作精神 |
| 研究室成員 | : | 目前成員 博士後研究員：Fabian Grassl 博士班：曾奎耀、黃昱齊、楊惠婷、丁彥如 碩士班：黃兟、李依玲、黃承佑 研究助理：黃品碩、鄭雅恩 實驗室管理：陳玉美 實驗室畢業生(畢業年)/目前工作 Ya-En Cheng 鄭雅恩(2024)/ Research Assitant, National Taiwan University Pi-Shiou Huang 黃品碩 （2024)/Research Assistant, National Taiwan University Wen-Hui Hsueh 薛文惠 （2024)/ Pei-Fang Chiu, 邱沛芳 (2023)/ Post-Doc, School of Pharmacy, University of Southern California Chen-Guang (Lucas) Zheng , 張晨光(2023)/Research Assistant, Academia Sinica/National Taiwan University Chung-Shun Lin, 林崇舜 (2023)/ Pharmacist, National Taiwan University Hospital Cheng-Ru Chen, 陳承儒 (2023)/ Analyst, Venture Capital Yi-Chi Wang, 王奕錡 (2022) / Scientist, ImmunAdd, Inc, Chun-Kai Chang, 張竣凱 (2022) / Military service, ImmunAdd, Inc. ) Yu-Pu Juang, 莊宇樸 (2022) / Post-Doc, College of Pharmacy, University of Michigan) Ru-Xian Lin, 林儒賢 (2021)/ Marketing, TTY BioPharma Yu-Ting Chou, 周郁庭 (2021) / CDE Reviewer, CDE Wan-Lan Gu, 辜琬嵐 (2021) / Pharmacist Chee-Wei Chaw, 刁志威 (2020)/ Marketing You-Yu Lin, 林佑諭 (2020) / Scientist, ImmunAdd, Inc. Jing-Xiu Cao, 曹景琇 (2019) / Pharmacist, Taipei Veterans General Hospital I-Chun Lin, 林怡君 (2019) / Marketing, Pfizer Zhen-Zhuo Teo, 張振卓 （2019）/ Associate Researcher, OBI Pharma Chia-Nan Chang, 張巧念 (2018) / CRA manager, CRO Hsiao-Wen Wang, 王筱雯 (2018) / Medical Writer, CRO Yen-Hsun Lai, 賴彥勳 (2018) / Lecture, National Defense Medical Center Ying-Ying Tsai, 蔡盈盈 (2018) / Scientist, Xantho Biotechnology Co., LTD I-Chen Liu, 劉奕辰 (2017)/ CDE reviewer, CDE Tsung-Yun Wong, 翁琮昀 (2016) / Ph.D. student, University of Minnesota Tzung-Sheng Lin, 林宗聖 (2016) / Post-Doc Researcher, Leibniz Universität Hannover Yue Hne, 方愉 (2016) / CRA, Norvatis Kuo-Ting Chen, 陳國庭 (2015) / Assistant Professor, National Dong-Hwa University How-Wen Cheng, 鄭皓文 (2014) / CMC mamanger, ImmunAdd Inc. Hui-Yi Yang, 楊慧怡 (2014) / DM, QPS Hsin-Min Hsiao, 蕭新民 (2013) / Pharmacist Yin-Jen Lu, 盧膺仁 (2013) / QA, AstraZeneca Hsien-Wei Yeh, 葉先偉 (2012) / Assitant Professor, UC Santa Cruz Yi-Bin Zeng, 曾依冰 (2012) / Assitant Manager, OBI Pharm Yi-Chun Chen, 陳逸宭 (2012) / CRA, Taiwan Liposome Company (TLC) Nikki Ya-Wen Liu, 劉雅雯 (2011) / CRA Ying-Hsin Wang, 王英馨 (2011) / MD, MSD Ming-Han Hsieh, 謝明翰 (2010) / Interior Designer Ting-Shuan Tang, 唐廷萱 (2010 summer) / Physician (Otorhinolaryngology), NTU Updated April, 2024 |
Discovery of 5-Hydroxy-1,4-naphthoquinone (Juglone) Derivatives as Dual Effective Agents Targeting Platelet-Cancer Interplay through Protein Disulfide Isomerase Inhibition
(2024-03-14) YU-PU JUANG ; Tsai, Ju Ying ; Gu, Wan Lan ; Hsu, Hui Ching ; Lin, Chao Lung ; Wu, Chin Chung ; PI-HUI LIANG
Effect of Sulfotyrosine and Negatively Charged Amino Acid of Leech-Derived Peptides on Binding and Inhibitory Activity Against Thrombin
(2024-02-01) Chen, Tzu-Yin ; Shyur, Eileen ; Ma, Tzu-Hsuan ; Wijeyewickrema, Lakshmi ; Lin, Sheng-Wei ; Kao, Mu-Rong ; PI-HUI LIANG ; Shie, Jiun-Jie ; Chuang, Er-Yuan ; Liou, Jing-Ping ; Hsieh, Yves S Y
Design, structure-activity relationships, and enzyme kinetic studies of tricyclic and tetracyclic coumarin-based sulfamates as steroid sulfatase inhibitors
(2023-09) Chiu, Pei-Fang ; Lin, I-Chun ; Lu, Yeh-Lin ; Chang, Chiao-Nien ; Chan, Hui-Yu ; Lin, Tzung-Shen ; Tsai, Keng-Chang ; Hsieh, Yves S Y ; MEI-JOU CHEN ; Lin, Mei-Hsiang ; PI-HUI LIANG
PD-L1 Enhanced by cis-Urocanic Acid on Langerhans Cells Inhibits Vγ4+ γδT17 Cells in Imiquimod-Induced Skin Inflammation
(2023-08) Yeh, Chen-Yun ; Su, Sheng-Han ; Tan, Yeh Fong ; Tsai, Tsen-Fang ; PI-HUI LIANG ; Kelel, Musin ; Weng, Hao-Jui ; Hsiao, Yu-Ping ; Lu, Chun-Hao ; Tsai, Ching-Hui ; Lee, Chih-Hung ; Clausen, Björn E ; Liu, Fu-Tong ; YUNG-LING LEE
Design, Synthesis, and Evaluation of Glucose Transporter Inhibitor-SN38 Conjugates for Targeting Colorectal Cancer
(2023-07-27) Chiu, Pei Fang ; Chang, Chun Kai ; Huang, Pin Shuo ; Lin, You Yu ; Lin, Chung Shun ; Yang, Hui Yi ; LIH-CHING HSU ; LINDA CHIA-HUI YU ; PI-HUI LIANG
(2024-03-14) YU-PU JUANG ; Tsai, Ju Ying ; Gu, Wan Lan ; Hsu, Hui Ching ; Lin, Chao Lung ; Wu, Chin Chung ; PI-HUI LIANG
Effect of Sulfotyrosine and Negatively Charged Amino Acid of Leech-Derived Peptides on Binding and Inhibitory Activity Against Thrombin
(2024-02-01) Chen, Tzu-Yin ; Shyur, Eileen ; Ma, Tzu-Hsuan ; Wijeyewickrema, Lakshmi ; Lin, Sheng-Wei ; Kao, Mu-Rong ; PI-HUI LIANG ; Shie, Jiun-Jie ; Chuang, Er-Yuan ; Liou, Jing-Ping ; Hsieh, Yves S Y
Design, structure-activity relationships, and enzyme kinetic studies of tricyclic and tetracyclic coumarin-based sulfamates as steroid sulfatase inhibitors
(2023-09) Chiu, Pei-Fang ; Lin, I-Chun ; Lu, Yeh-Lin ; Chang, Chiao-Nien ; Chan, Hui-Yu ; Lin, Tzung-Shen ; Tsai, Keng-Chang ; Hsieh, Yves S Y ; MEI-JOU CHEN ; Lin, Mei-Hsiang ; PI-HUI LIANG
PD-L1 Enhanced by cis-Urocanic Acid on Langerhans Cells Inhibits Vγ4+ γδT17 Cells in Imiquimod-Induced Skin Inflammation
(2023-08) Yeh, Chen-Yun ; Su, Sheng-Han ; Tan, Yeh Fong ; Tsai, Tsen-Fang ; PI-HUI LIANG ; Kelel, Musin ; Weng, Hao-Jui ; Hsiao, Yu-Ping ; Lu, Chun-Hao ; Tsai, Ching-Hui ; Lee, Chih-Hung ; Clausen, Björn E ; Liu, Fu-Tong ; YUNG-LING LEE
Design, Synthesis, and Evaluation of Glucose Transporter Inhibitor-SN38 Conjugates for Targeting Colorectal Cancer
(2023-07-27) Chiu, Pei Fang ; Chang, Chun Kai ; Huang, Pin Shuo ; Lin, You Yu ; Lin, Chung Shun ; Yang, Hui Yi ; LIH-CHING HSU ; LINDA CHIA-HUI YU ; PI-HUI LIANG
Establishment of New Generation Probiotics/Postbiotics to Modulate Metabolic-Immune Function for Medical/Health Management( I )
(2024-05-01～) YEN-HSUAN NI
Isolation, Biosynthesis Exploration and C-H Bond-Activation to Afford Triterpenoid Saponins as Immunomodulating Agents( III )
(2023-08-01～) PI-HUI LIANG
Impurities Analysis of Drugs and Structure Characterization and Composition Analysis of Herbal Medicines and Metabolites( III )
(2023-02-01～) PI-HUI LIANG
Isolation, Biosynthesis Exploration and C-H Bond-Activation to Afford Triterpenoid Saponins as Immunomodulating Agents( II )
(2022-08-01～) PI-HUI LIANG
Impurities Analysis of Drugs and Structure Characterization and Composition Analysis of Herbal Medicines and Metabolites( II )
(2022-02-01～) PI-HUI LIANG
(2024-05-01～) YEN-HSUAN NI
Isolation, Biosynthesis Exploration and C-H Bond-Activation to Afford Triterpenoid Saponins as Immunomodulating Agents( III )
(2023-08-01～) PI-HUI LIANG
Impurities Analysis of Drugs and Structure Characterization and Composition Analysis of Herbal Medicines and Metabolites( III )
(2023-02-01～) PI-HUI LIANG
Isolation, Biosynthesis Exploration and C-H Bond-Activation to Afford Triterpenoid Saponins as Immunomodulating Agents( II )
(2022-08-01～) PI-HUI LIANG
Impurities Analysis of Drugs and Structure Characterization and Composition Analysis of Herbal Medicines and Metabolites( II )
(2022-02-01～) PI-HUI LIANG